Journal of Clinical Immunology and Allergy

The relationship between asthma risk factors and its severity in children with asthma referred to asthma and allergy clinics

Introduction: Asthma reversible obstruction of small and large airways is different due to increased sensitivity to immunological stimuli, which manifests itself in the form of frequent and intermittent attacks of cough, shortness of breath, chest heaviness and wheezing. Both the prevalence and severity of asthma have increased in many countries in recent decades. According to statistics, the prevalence of this disease in the world is 3-35%. This statistic in Iran is between 7.2-4.3% and the average prevalence of asthma symptoms in the whole country is 14.1%

Materials and methods: Asthma is the most common chronic disease in children and is less common in adults. About 90% of cases of asthma occur in childhood, which indicates the effect of internal and environmental risk factors for asthma in childhood. These factors include genetic predisposition, increased airway response, atopy, gender, and possibly race.

Results: Out of 200 children with asthma studied, (53.5%) were 107 boys and (46.5%) were 93 girls. The mean age of the total number of children was 8.8 2 2.1 years.

Discussion: This study investigated the relationship between asthma risk factors such as obesity and disease severity in 200 children with asthma in Urmia. Our findings showed that 53.5% of children with mild asthma, 34.5% of children with moderate asthma and 12% of children with severe asthma.

Conclusion: In this descriptive analytical cross-sectional study to investigate the relationship between asthma risk factors and its severity in children with asthma referred to the asthma and allergy clinics of Urmia university of medical sciences during the years 1300-1499, the findings show 53.5% of children with mild asthma, 34.5% of children with moderate asthma and 12% of children with severe asthma. Also, 82% of children had a normal BMI and 18% were obese.

Author(s): Hamidreza Houshmand*

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