Abstract

The role of interleukin 33 in patients with allergic diseases who has a positive result of total and specific IgE

Introduction: Allergic diseases affect a large group of population and the common types were asthma, rhinitis, and urticaria and newly found that IL-33 playing an important role in the pathogenicity of allergic diseases.

Objectives: The main goal of this research to evaluate the levels of IL-33 in adult patients has real allergic diseases (asthma, rhinitis, and urticaria) through the detection of both positive assays of total and specific IgE of allergic diseases.

Methods: The total and specific immunoglobulin E (IgE) and IL-33 were determined in the serum of three types of allergic patients and healthy controls.

Results: There was a highly significantly higher concentration of IgE and IL- 33 in the serum of patients with allergic diseases. Serum IL-33 and total IgE concentration are clearly statistically highly significant increases in three groups of patients (Rhinitis, Asthma, Urticaria) compared with healthy control (p< 0.001). No significant correlation between IL-33 levels and total IgE in four groups.

Conclusion: Our results show a significantly higher concentration in serum level IL- 33 of patients with three types of allergic diseases (asthma, rhinitis, and urticaria).

Keywords

interleukin 33, allergic diseases, specific IgE.


Author(s):

Ghanyia Jasim Shanyoor



Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
Awards Nomination 17+ Million Readerbase
Recommended Conferences
Google scholar citation report
Citations : 16

Journal of Clinical Immunology and Allergy received 16 citations as per google scholar report

Abstracted/Indexed in
  • Google Scholar
  • Directory of Research Journal Indexing (DRJI)
  • WorldCat
  • Publons
  • Secret Search Engine Labs

View More »

Flyer image