neration of neutrophil extracellular traps (NETs), but also modulate the immune response according to the
microenvironment and the cell-cell interactions. As it is known, NETs are formed by chromatin and granular proteins
which after stimulation are released to the extracellular environment. NETs have not only been involved as defence
mechanisms, but they have also been linked to tissue damage, thrombosis, cancer immune editing and autoimmunity.
Poly morpho nuclear neutrophils (PMNs) activated in vitro may express molecules normally associated with antigen
presenting cells (APCs).
Ivon T C Novak